Antipsychotics, however, fail to significantly ameliorate the negative symptoms and cognitive dysfunction.

It has been shown to delay the onset of disease in the NPC mouse, and published data from a multi-center clinical trial of Miglustat in the United States and England and from case reports suggests that it may ameliorate the course of human NPC.

Distributed methods, such as Rosetta@home, have attempted to ameliorate this by recruiting individuals who then volunteer idle home computer time in order to process data.

Researchers today generally endorse this view, noting that parents can ameliorate this response by being vigilant to favoritism and by taking appropriate preventative steps.